ADDRES Lab Photo
The Advanced Drug Delivery Research (ADDRES) Laboratory at Northeastern University is headed by Dr. Rebecca Carrier of Northeastern’s Department of Chemical Engineering.

The ADDRES Lab studies interactions between materials and biological systems, with a current focus on the intestinal environment, via development of theoretical and tissue-engineered cell culture models. Computational models (molecular and macroscopic) predict what drug delivery systems will enhance absorption of a compound with specific physical and chemical properties. Macroscopic systems-based models of the intestinal drug delivery environment are in the form of mass balances and kinetic equations describing drug release, dissolution, precipitation, and absorption. Mechanistic studies are conducted to enhance fundamental understanding of these processes. Our tissue engineering focus is on developing a biomimetic scaffold with crypt-villus structure for intestinal epithelial cell culture.
Areas of Research

Computational modelling of intestinal drug delivery environmentImg1
Computational modeling of the intestinal drug delivery environment to predict the influence of delivery agents on oral drug absorption.

Analysis and modulation of mucus barrier propertiesImg2
Analysis of transport through intestinal mucus for understanding drug-mucus interactions and how they are influenced by delivery agents.

Biomaterials for regenerative medicineImg3
Development of biomaterials for intestinal and retinal tissue engineering.

Home | Research | People | Laboratory | Publications | Collaborators | Passion for Science | Photos | Links | Contact

Northeastern University, Deparment of Chemical Engineering, Advanced Drug Delivery Research Laboratory @ 2009 All rights Reserved